CodeWeavers, the company that works on Proton with Valve and supports Wine development, has announced the released of CrossOver 22.0.0. This is their special proprietary interface for helping users across Linux, macOS and Chrome OS work with applications and games designed for Windows on their platform of choice.
One of the big new things about this release is the refreshed user interface, with the last upgrade to the UI being CrossOver 15 many years ago and no redesign since CrossOver 9. They said their goal with the redesign was to make it "more intuitive to use and offer a more modern look and feel" enabling "users to find the things they need to do most often and to bring the CrossOver interface in line with our branding".
Some of the other big changes to come along with the UI redesign include extensive changes to the installation process, an updated search function. What you get is a more guided install path for many applications, while also still letting you override things to your liking.
They also revamped the bottle view, where you actually install things. Plus there's a new Home view, which is a mash up of their old All Bottles and Favourites views.
CrossOver 22 includes Wine 7.7, Wine Mono 7.2.0 and vkd3d 1.4. They say you also get initial support for DirectX 12 with a "handful" of games running well along with fixes to Office 2016/365 bugs. Seems like they might be having issues with GTA Online bans though, so be warned.
Why use CrossOver instead of something like Bottles? Well, it's largely all about support. You're paying for supported software, while also directly helping Wine and Proton development because CodeWeavers sponsor Wine. CrossOver also has many paid staff working on it, with more quality assurance testing so there's that too. It comes down to what you prefer - choices are great.