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Buckshot Roulette meets Big Pharma in the latest game from Free Lives, and it's as grim as you might expect it to be with that sort of description.

Two test subjects. One twisted medical trial. Only one leaves. Each round you'll be presented with a selection of pills. Some are helpful, some are harmful, and some mean instant death. Outlast your opponent in order to win. According to what I was sent over an early prototype of Side Effects went viral on itch.io and YouTube, drawing millions of views and hundreds of thousands of plays.

Here's the demo trailer below:

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Highlights:

  • Resist - Every pill impacts your resistance. Manage it wisely: zero resistance means death.
  • Experiment - Between rounds, you can choose from a range of experimental items and treatments that can shift the odds in your favor, from vaccines to mouth clamps.
  • You’re not alone - The other patient wants to outlast you. They’ll bluff, adapt, and use everything at their disposal to keep breathing one dose longer than you.

This demo version medical trial includes:

  • A single player mode.
  • 10+ items.
  • 6 pill types to test.
  • New mechanics (item re-roll etc).

The full version will feature

  • Extended single player mode.
  • Free Healthcare (endless mode).
  • A multiplayer mode (2-4 players!).
  • 15+ unique items.
  • 6 pill types to test.

SIDE EFFECTS | Release Date: 21st November 2025

Official links:

Article taken from GamingOnLinux.com.
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I am the owner of GamingOnLinux. After discovering Linux back in the days of Mandrake in 2003, I constantly checked on the progress of Linux until Ubuntu appeared on the scene and it helped me to really love it. You can reach me easily by emailing GamingOnLinux directly.
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OK, this is kind of an incredible idea, but I don't understand why I'd want to experience it.
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